Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer genes and cancer stem cells in tumorigenesis: Evolutionary deep homology and controversies

4 Apr 2022

Abstract excerpt

In the past, contradictory statements have been made about the age of cancer genes. While phylostratigraphic studies suggest that cancer genes emerged during the transitional period from unicellularians (UC) to early metazoans (EM), life cycle studies suggest that they arose earlier. This controversy could not be resolved. Phylostratigraphic methods use data from somatic tumor gene collections containing or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Protist diversity and phylogeny

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35873035
DOI: 10.1016/j.gendis.2022.03.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer genes and cancer stem cells in tumorigenesis: Evolutionary deep homology and controversiesPMID 35873035Read ↗

Re-evaluation of the Concept of Cancer Stem Cells and Cancer Stemness in the Light of Evolutionary Cancer Cell Biology (ECCB)Semantic proximity Read ↗

Evolutionary, Non-Mutational Cancers Cannot Be Considered AtavisticSemantic proximity Read ↗

Phylostratigraphic analysis of tumor and developmental transcriptomes reveals relationship between oncogenesis, phylogenesis and ontogenesisSemantic proximity Read ↗

Introduction to Evolutionary Cancer Cell Biology (Eccb) and Ancestral Cancer GenomicsSemantic proximity Read ↗

Understanding Cancer from an Evolutionary Perspective; DSCD Cells as Cell-of-Origin in Non-Mutational Sporadic CancersSemantic proximity Read ↗

Re-Evaluating Cancer Stem Cells (CSCs) and Polyploid Giant Cancer Cells (PGCCs) in the Light of Evolutionary Cancer Cell Biology ECCBSemantic proximity Read ↗

Introduction to Evolutionary Cancer Cell Biology (ECCB) and Ancestral Cancer GenomicsSemantic proximity Read ↗

Reverting to single-cell biology: The predictions of the atavism theory of cancer.Semantic proximity Read ↗

From Multicellular Constraint to Unicellular Control: Cancer Evolves by Ancient Mechanisms of Genome Reconstruction, Repair, and ExpansionSemantic proximity Read ↗

The Eco-Evolutionary Ground State Theory of Cancer and Why Cancer DevelopsSemantic proximity Read ↗

The Enigma of Cancer Polyploidy as Deciphered by Evolutionary Cancer Cell Biology (ECCB)Semantic proximity Read ↗

aCLS cancers: Genomic and epigenetic changes transform the cell of origin of cancer into a tumorigenic pathogen of unicellular organization and lifestyle.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.