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Understanding Cancer from an Evolutionary Perspective; DSCD Cells as Cell-of-Origin in Non-Mutational Sporadic Cancers

2023-12-26

Abstract excerpt

<h4>Background: </h4> One of the most astounding discoveries of recent times is the recognition that cancer embodies a transition from a higher level of metazoan cell organization to a more foundational pre-metazoic state. This shift is steered by genes housed within the ancestral genome compartment, pervasive across all metazoan genomes, encompassing humans, and governed by a pre-metazoic gene regulatory mechanis...

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Literature Corpus work: ffa46b9e-02c8-5d2d-a9e8-89e0944a5a68
DOI: 10.20944/preprints202308.1688.v2

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