Article

Statins and antidepressants induce similar <i>in vitro</i> gene expression responses

2022-03-31

Abstract excerpt

<h4>Background</h4> Based on observational studies and small-scale randomized controlled trials, it is uncertain whether cholesterol-lowering statins have any beneficial or adverse effects on depressive symptoms. In this study we investigate this question using a genomics approach. <h4>Methods</h4> To compare the pharmacological effects of statin and antidepressant exposure and identify commonly perturbed biologic...

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Literature Corpus work: e693b6ba-0a80-58d5-aa13-3a29499a5e8d
DOI: 10.1101/2022.03.27.22273017

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