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Multi-continental detection of <i>Streptococcus pyogenes</i> M1 <sub>UK</sub> : Impact of ssrA SNP on SpeA expression in ancestral and M1 <sub>UK</sub> isolates

2023-05-02

Abstract excerpt

The Streptococcus pyogenes M1 UK lineage, characterised by an intrinsic ability to express SpeA toxin and defined by 27 single nucleotide polymorphisms in the core genome, dominates the population of emm 1 S. pyogenes isolates throughout Europe, Canada, South America, Japan and Oceania. While not the sole deterministic factor, enhanced SpeA expression is likely to have contributed to M1 UK lineage expansion,...

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Literature Corpus work
e65c4cd1-560d-5b59-8042-db352a088423
DOI
10.1101/2023.04.30.538858
Open publication

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Multi-continental detection of <i>Streptococcus pyogenes</i> M1 <sub>UK</sub> : Impact of ssrA SNP on SpeA expression in ancestral and M1 <sub>UK</sub> isolatesDOI 10.1101/2023.04.30.538858
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