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Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study

10 Sept 2019

Abstract excerpt

Background Since 2014, England has seen increased scarlet fever activity unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected elevation in invasive Streptococcus pyogenes infections. We describe the molecular epidemiological investigation of these events. Methods We analysed changes in S pyogenes emm genotypes, and notifications of scarlet fever and invasive...

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PMID: 31519541
DOI: 10.1016/s1473-3099(19)30446-3

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