Article

Characterisation of emergent toxigenic M1 <sub>UK</sub> <i>Streptococcus pyogenes</i> and associated sublineages

2022-12-28

Abstract excerpt

Emm 1 Streptococcus pyogenes is a successful, globally-distributed epidemic clone that is regarded as inherently invasive. An emm 1 sublineage, M1 UK , that expresses increased SpeA toxin, was associated with increased scarlet fever and invasive infections in England in 2015/2016. Defined by 27 SNPs in the core genome, M1 UK is now dominant in England. To more fully characterise M1 UK , we undertook comparati...

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Literature Corpus work: 1f1d5d26-2257-54a0-ae5e-b6a9a023d33d
DOI: 10.1101/2022.12.27.522030

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