Article

Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype

2024-02-09

Abstract excerpt

<title>Abstract</title> <p>Dysregulation of development, migration, and function of interneurons, collectively termed interneuronopathies, have been proposed as a shared mechanism for autism spectrum disorders (ASDs) and childhood epilepsy. Neuropilin-2 (Nrp2), a candidate ASD gene, is a critical regulator of interneuron migration from the median ganglionic eminence (MGE) to the pallium, including the hippocampus...

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Literature Corpus work: e65b0fec-94b9-5e46-bae4-89854d07157f
DOI: 10.21203/rs.3.rs-3922129/v1

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