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Article

Interneuronopathies and their role in early life epilepsies and neurodevelopmental disorders

13 May 2017

Abstract excerpt

GABAergic interneurons control the neural circuitry and network activity in the brain. The advances in genetics have identified genes that control the development, maturation and integration of GABAergic interneurons and implicated them in the pathogenesis of epileptic encephalopathies or neurodevelopmental disorders. For example, mutations of the Aristaless-Related homeobox X-linked gene (ARX) may result in...

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PMID: 29062978
DOI: 10.1002/epi4.12062

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