Article

Reduced Hippocampal Inhibition and Enhanced Autism-Epilepsy Comorbidity in Mice Lacking Neuropilin 2

2021-06-11

Abstract excerpt

The neuropilin receptors and their secreted semaphorin ligands play key roles in brain circuit development by regulating numerous crucial neuronal processes, including the maturation of synapses and migration of GABAergic interneurons. Consistent with its developmental roles, the neuropilin 2 ( Nrp2 ) locus contains polymorphisms in patients with autism spectrum disorder (ASD). Nrp2 deficient mice show autism-l...

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Literature Corpus work: 3bb9430f-47a7-50d8-ace9-f561c3e0a28f
DOI: 10.1101/2021.06.11.448071

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