Article

Recombinant protein delivery enables modulation of the phototransduction cascade in mouse retina

2022-11-13

Abstract excerpt

Retinal dystrophies of genetic origin are often associated with mutations in the genes involved in the phototransduction cascade in photoreceptors, a paradigmatic signaling pathway mediated by G protein-coupled receptors. Photoreceptor viability is strictly dependent on the levels of the second messengers cGMP and Ca 2+ . Here we explored the possibility of modulating the phototransduction cascade in mouse rods u...

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Identifiers and source

Literature Corpus work: e656778a-4c88-519e-b032-d1644a52a151
DOI: 10.1101/2022.11.10.516027

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