Article

Reactivating the phototransduction cascade by universally applicable gene therapy preserves retinal function in Rod-Cone dystrophy

2022-01-17

Abstract excerpt

<title>Abstract</title> Rod-cone dystrophy (RCD), also known as retinitis pigmentosa, is a group of inherited disorders characterized by rod degeneration followed by degeneration of peripheral cones, leaving patients with tunnel vision in mid stages and blindness in the latest stages. Previous studies expressed microbial chloride pumps, in degenerating cone photoreceptors to restore these cells’ activity and p...

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Literature Corpus work: 0aa84f9c-ee52-581f-86a0-572b68c24486
DOI: 10.21203/rs.3.rs-1189099/v1

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