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Elevated phagocytic capacity directs innate spinal cord repair

2024-06-13

Abstract excerpt

<h4>ABSTRACT</h4> Immune cells elicit a continuum of transcriptional and functional states after spinal cord injury (SCI). In mammals, inefficient debris clearance and chronic inflammation impede recovery and overshadow pro-regenerative immune functions. We found that, unlike mammals, zebrafish SCI elicits transient immune activation and efficient debris clearance, without causing chronic inflammation. Single-cel...

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Literature Corpus work
e64c53ec-a24f-50d5-b780-010249470fbe
DOI
10.1101/2024.06.11.598515
Open publication

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Elevated phagocytic capacity directs innate spinal cord repairDOI 10.1101/2024.06.11.598515
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