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Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratification

7 Feb 2024

Abstract excerpt

INTRODUCTION: Blood protein biomarkers demonstrate potential for Alzheimer's disease (AD) diagnosis. Limited studies examine the molecular changes in AD blood cells. METHODS: Bulk RNA-sequencing of blood cells was performed on AD patients of Chinese descent (n = 214 and 26 in the discovery and validation cohorts, respectively) with normal controls (n = 208 and 38 in the discovery and validation cohorts,...

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PMID: 38323937
DOI: 10.1002/alz.13691

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