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Article

Toward an Alzheimer's disease diagnosis via high‐resolution blood gene expression

1 Jan 2010

Abstract excerpt

BACKGROUND: There is a significant need for reliable molecular biomarkers to aid in Alzheimer's disease (AD) clinical diagnosis. METHODS: We performed a genome-wide investigation of the human transcriptome, taking into account the discriminatory power of splice variations from the blood of 80 AD patients and 70 nondemented control (NDC) individuals. RESULTS: We characterized a blood RNA signature composed of 170...

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PMID: 20129318
DOI: 10.1016/j.jalz.2009.07.001

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