Article
RAD-Blood: a database to identify RNAs in blood as potential biomarkers of Alzheimer's disease by integrating bulk- and single-cell transcriptome profile
2023-02-27
Abstract excerpt
<h4>Background: </h4> The early diagnosis of Alzheimer's disease (AD) in large-scale high-risk population is a major challenge. Blood-based biomarkers could enable widespread testing for AD. RNA-seq technology is becoming an effective method in investigating diagnostic biomarkers for diseases, but platforms exploring RNA-seq data in AD blood are lacking. Methods We collected the raw RNA-seq data in the blood of A...
Topics
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- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Genetics and Neurodevelopmental Disorders
- Machine Learning in Bioinformatics
- Neuroinflammation and Neurodegeneration Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- f21fc073-5086-55a8-b79d-5cc58203f0f0
- DOI
- 10.21203/rs.3.rs-2619861/v1
