Article

Genome-wide tandem repeat expansions contribute to schizophrenia risk

2021-12-21

Abstract excerpt

Tandem repeat expansions (TREs) can cause neurological diseases but their impact in schizophrenia is unclear. Here we analyzed genome sequences of adults with schizophrenia and found that they have a higher burden of TREs that are near exons and rare in the general population, compared with non-psychiatric controls. These TREs are disproportionately found at loci known to be associated with schizophrenia from geno...

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Literature Corpus work: e6127d8d-f2b6-5458-8eb0-663b2b32ccf7
DOI: 10.1101/2021.12.17.21267642

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