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Article

The genetic architecture of schizophrenia: review of large-scale genetic studies.

Journal of human genetics - 1 Mar 2023

Kato Hidekazu, Kimura Hiroki, Kushima Itaru, Takahashi Nagahide, Aleksic Branko, Ozaki Norio

Abstract excerpt

Schizophrenia is a complex and often chronic psychiatric disorder with high heritability. Diagnosis of schizophrenia is still made clinically based on psychiatric symptoms; no diagnostic tests or biomarkers are available. Pathophysiology-based diagnostic scheme and treatments are also not available. Elucidation of the pathogenesis is needed for development of pathology-based diagnostics and treatments. In the...

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PMID: 35821406
DOI: 10.1038/s10038-022-01059-4

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