Article

Topological signatures in regulatory network enable phenotypic heterogeneity in small cell lung cancer

2020-11-01

Abstract excerpt

Phenotypic (non-genetic) heterogeneity has significant implications for development and evolution of organs, organisms, and populations. Recent observations in multiple cancers have unravelled the role of phenotypic heterogeneity in driving metastasis and therapy recalcitrance. However, the origins of such phenotypic heterogeneity are poorly understood in most cancers. Here, we investigate a regulatory network und...

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Literature Corpus work: e5fe7e4f-5d90-5458-b21c-ecbaae5560b9
DOI: 10.1101/2020.10.30.362228

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