Article

The impact of blood MCP-1 levels on Alzheimer’s disease with genetic variation of UNC5C and NAV3 loci

2023-09-28

Abstract excerpt

<h4>Background: </h4> Previous study shows that monocyte chemoattractant protein-1 (MCP-1), which is implicated in the peripheral proinflammatory cascade and blood-brain barrier (BBB) disruption, modulates the genetic risks of AD in established AD loci. Methods In this study, we hypothesized that blood MCP-1 impacts the AD risk of genetic variants beyond known AD loci. We thus performed a genome-wide association...

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Literature Corpus work: e5fb4998-939f-5eb4-9506-bb22fe0da8c6
DOI: 10.21203/rs.3.rs-3376348/v1

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