Article

A Continuous Extension of Gene Set Enrichment Analysis using the Likelihood Ratio Test Statistics Identifies VEGF as a Candidate Pathway for Alzheimer’s disease

2023-08-23

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease involves brain pathologies such as amyloid plaque depositions and hyperphosphorylated tau tangles and is accompanied by cognitive decline. Identifying the biological mechanisms underlying disease onset and progression based on quantifiable phenotypes will help understand the disease etiology and devise therapies. <h4>Objective</h4> Our objective was to identify molecular p...

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Literature Corpus work: 38362c9e-b3fa-54b9-aae6-d4591d9b8880
DOI: 10.1101/2023.08.22.554319

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