Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VEGF-A-related genetic variants protect against Alzheimer's disease.

Aging - 28 Mar 2022

Petrelis Alexandros M, Stathopoulou Maria G, Kafyra Maria, Murray Helena, Masson Christine, Lamont John, Fitzgerald Peter, Dedoussis George, Yen Frances T, Visvikis-Siest Sophie

Abstract excerpt

The Apolipoprotein E (APOE) genotype has been shown to be the strongest genetic risk factor for Alzheimer's disease (AD). Moreover, both the lipolysis-stimulated lipoprotein receptor (LSR) and the vascular endothelial growth factor A (VEGF-A) are involved in the development of AD. The aim of the study was to develop a prediction model for AD including single nucleotide polymorphisms (SNP) of APOE, LSR and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Vascular Endothelial Growth Factor A
Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Genotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 35347084
DOI: 10.18632/aging.203984
PMCID: PMC9004571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VEGF-A-related genetic variants protect against Alzheimer's disease.PMID 35347084Read ↗

Epistatic interaction of apolipoprotein E and lipolysis-stimulated lipoprotein receptor genetic variants is associated with Alzheimer's disease.Semantic proximity Read ↗

A Continuous Extension of Gene Set Enrichment Analysis using the Likelihood Ratio Test Statistics Identifies VEGF as a Candidate Pathway for Alzheimer’s diseaseSemantic proximity Read ↗

Analysis of the causal relationship between five chosen factors and early-onset Alzheimer's disease: A Mendelian randomization study.Semantic proximity Read ↗

Circulating Endothelial Progenitor Cells Reduce the Risk of Alzheimer’s DiseaseSemantic proximity Read ↗

VEGFB is a potential therapeutic target for Alzheimer's disease: Insights from integrative multi-omics analysis.Semantic proximity Read ↗

Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.Semantic proximity Read ↗

Vascular endothelial growth factor polymorphisms and risk of Alzheimer's disease: a meta-analysis.Semantic proximity Read ↗

Immune response and endocytosis pathways are associated with the resilience against Alzheimer’s diseaseSemantic proximity Read ↗

Immune response and endocytosis pathways are associated with the resilience against Alzheimer’s DiseaseSemantic proximity Read ↗

Shared genes between Alzheimer’s disease and ischemic strokeSemantic proximity Read ↗

The role of vascular dementia associated genes in patients with Alzheimer's disease: A large case–control study in the Chinese populationSemantic proximity Read ↗

Computational prediction of high-risk non-synonymous SNPs in human ApoE and their structural impact on amyloid-β interaction in Alzheimer’s disease pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.