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Article

Family-based association analysis of NAV2 gene with the risk and age at onset of Alzheimer's disease.

Journal of neuroimmunology - 15 Sept 2017

Wang Ke-Sheng, Liu Ying, Xu Chun, Liu Xuefeng, Luo Xingguang

Abstract excerpt

The neuron navigator 2 (NAV2) gene is highly expressed in brain and involved in the nervous system development and may play a role in Alzheimer's disease (AD). We aimed to investigate the associations of 317 single-nucleotide polymorphisms (SNPs) in the NAV2 gene with the risk and age at onset (AAO) of AD using a family-based sample (1266 AD cases and 1279 healthy relatives). Association with the risk of AD was...

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Source

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Identifiers

PMID: 28778446
DOI: 10.1016/j.jneuroim.2017.06.010
PMCID: PMC6167010

Genes

NAV2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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