Article
The Impact of UNC5C Genetic Variations on Neuroimaging in Alzheimer's Disease.
Molecular neurobiology - 1 Dec 2016
Sun Jia-Hao, Wang Hui-Fu, Zhu Xi-Chen, Yu Wan-Jiang, Tan Chen-Chen, Jiang Teng, Tan Meng-Shan, Tan Lan, Yu Jin-Tai
Abstract excerpt
UNC5C, which is a transmembrane receptor for netrin-1 to trigger the apoptosis, has been confirmed as a new risk factor for Alzheimer's disease (AD) recently. However, there is lack of the evidence on the brain structure associated with the polymorphisms of UNC5C in AD. The objective of this study is to investigate the influence of UNC5C loci on the neuroimaging of strategic regions of AD. In 812 subjects from...
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