Article

Endothelial CCR6 Expression Due to FLI1 Deficiency Contributes to Vasculopathy Associated with Systemic Sclerosis

2021-06-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> We have recently demonstrated that serum CCL20 levels positively correlate with mean pulmonary arterial pressure in patients with systemic sclerosis (SSc). Considering a proangiogenic effect of CCL20 on endothelial cells via CCR6, the CCL20/CCR6 axis may contribute to the development of SSc vasculopathy. Therefore, we explored this hypothesis using clinical samp...

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Literature Corpus work: e5df4d14-7230-54a5-9d7f-85f66ec718ef
DOI: 10.21203/rs.3.rs-642879/v1

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