Article
Fli1 deficiency contributes to the suppression of endothelial CXCL5 expression in systemic sclerosis.
Archives of dermatological research - 1 May 2014
Ichimura Yohei, Asano Yoshihide, Akamata Kaname, Takahashi Takehiro, Noda Shinji, Taniguchi Takashi, Toyama Tetsuo, Aozasa Naohiko, Sumida Hayakazu, Kuwano Yoshihiro, Yanaba Koichi, Tada Yayoi, Sugaya Makoto, Sato Shinichi, Kadono Takafumi
Abstract excerpt
CXCL5 is a member of CXC chemokines with neutrophilic chemoattractant and pro-angiogenic properties, which has been implicated in the pathological angiogenesis of rheumatoid arthritis and inflammatory bowel diseases. Since aberrant angiogenesis is also involved in the developmental process of systemic sclerosis (SSc), we herein measured serum CXCL5 levels in 63 SSc and 18 healthy subjects and investigated their...
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