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Article

Epigenetic suppression of Fli1, a potential predisposing factor in the pathogenesis of systemic sclerosis.

The international journal of biochemistry & cell biology - 1 Oct 2015

Asano Yoshihide

Abstract excerpt

Systemic sclerosis (SSc) is a multisystem connective tissue disease featured by immune abnormalities, vasculopathy and tissue fibrosis with unknown etiology. A series of studies on disease-susceptibility genes and twins have demonstrated the association of genetic factors with autoimmunity and disease severity and the contribution of environmental factors to the induction of clinical features in this disease....

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Identifiers

PMID: 26055516
DOI: 10.1016/j.biocel.2015.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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