Article

Patterns of selection reveal shared molecular targets over short and long evolutionary timescales

2017-12-06

Abstract excerpt

Standing and de novo genetic variants can both drive adaptation to environmental changes, but their relative contributions and interplay remain poorly understood. Here we investigated the dynamics of drug adaptation in yeast populations with different levels of standing variation by experimental evolution coupled with time-resolved sequencing and phenotyping. We found a doubling of standing variation alone boost...

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Literature Corpus work: e5837491-395b-5fa9-b3c2-06fd1b2751dd
DOI: 10.1101/229419

Open publication

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