Article
Combining experimental evolution with next-generation sequencing: a powerful tool to study adaptation from standing genetic variation.
Heredity - 1 May 2015
Schlötterer C, Kofler R, Versace E, Tobler R, Franssen S U
Abstract excerpt
Evolve and resequence (E&R) is a new approach to investigate the genomic responses to selection during experimental evolution. By using whole genome sequencing of pools of individuals (Pool-Seq), this method can identify selected variants in controlled and replicable experimental settings. Reviewing the current state of the field, we show that E&R can be powerful enough to identify causative genes and possibly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
