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Article

Complex, multimodal behavioral profile of the <i>Homer1 </i>knockout mouse

26 May 2006

Abstract excerpt

Proteins of the Homer1 immediate early gene family have been associated with synaptogenesis and synaptic plasticity suggesting broad behavioral consequences of loss of function. This study examined the behavior of male Homer1 knockout (KO) mice compared with wild-type (WT) and heterozygous mice using a battery of 10 behavioral tests probing sensory, motor, social, emotional and learning/memory functions. KO mice...

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PMID: 16734773
DOI: 10.1111/j.1601-183x.2006.00240.x

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