Article

Characterizing Highly Conserved Fragments in 3’UTRs via Computational and Transfer Learning Approaches

2026-01-20

Abstract excerpt

<h4>ABSTRACT</h4> 3’ untranslated regions (3’ UTRs) serve as regulatory platforms that modulate translation, mRNA localization, and stability through the binding of regulators, such as RNA-binding proteins (RBPs) and miRNAs, in a sequence-specific manner. These vital binding sites are often identified through orthologous regions among species. A separate but related discovery is the ultraconserved elements (UCEs)...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e557a97e-311b-588c-8904-c2437899dc8a
DOI: 10.64898/2026.01.19.700376

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterizing Highly Conserved Fragments in 3’UTRs via Computational and Transfer Learning ApproachesDOI 10.64898/2026.01.19.700376Read

The Functional Map of Ultraconserved Regions in Humans, Mice and RatsSemantic proximity Read

Leveraging omic features with F3UTER enables identification of unannotated 3’UTRs for synaptic genesSemantic proximity Read

Predicting functional UTR variants by integrating region-specific features.Semantic proximity Read

A systematic delineation of 3′UTR regulatory elements and their contextual associationsSemantic proximity Read

Investigating the performance of foundation models on human 3’UTR sequencesSemantic proximity Read

utR.annotation: a tool for annotating genomic variants that could influence post-transcriptional regulationSemantic proximity Read

Massively Parallel Analysis of Human 3′ UTRs Reveals that AU-Rich Element Length and Registration Predict mRNA DestabilizationSemantic proximity Read

G4mer: An RNA language model for transcriptome-wide identification of G-quadruplexes and disease variants from population-scale genetic dataSemantic proximity Read

Genome-wide functional screen of 3’UTR variants uncovers causal variants for human disease and evolutionSemantic proximity Read

Human 5′ UTR design and variant effect prediction from a massively parallel translation assaySemantic proximity Read

Differences in 5’untranslated regions highlight the importance of translational regulation of dosage sensitive genesSemantic proximity Read

A Two-Stage Interpretable Framework for Predicting Plant-Derived Small RNA Targets on Human 3’UTRsSemantic proximity Read