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Article

Predicting functional UTR variants by integrating region-specific features.

Briefings in bioinformatics - 23 May 2024

Li Guangyu, Wu Jiayu, Wang Xiaoyue

Abstract excerpt

The untranslated region (UTR) of messenger ribonucleic acid (mRNA), including the 5'UTR and 3'UTR, plays a critical role in regulating gene expression and translation. Variants within the UTR can lead to changes associated with human traits and diseases; however, computational prediction of UTR variant effect is challenging. Current noncoding variant prediction mainly focuses on the promoters and enhancers,...

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Identifiers

PMID: 38783704
DOI: 10.1093/bib/bbae248
PMCID: PMC11116830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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