Article

Differences in 5’untranslated regions highlight the importance of translational regulation of dosage sensitive genes

2023-05-15

Abstract excerpt

<h4>Background</h4> Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known about the reasons for this variation in humans. Here, we set out to determine whether this variation, specifically in 5’UTRs, correlates with gene dosage sensitivity. <...

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Literature Corpus work: 1175df49-bb8b-5f50-bdac-01680e64280f
DOI: 10.1101/2023.05.15.540809

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