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Mutations in <i>emb</i> B406 are associated with low-level ethambutol resistance in Canadian <i>Mycobacterium tuberculosis</i> isolates

2023-03-09

Abstract excerpt

<h4>Background</h4> In Mycobacterium tuberculosis , molecular predictions of ethambutol resistance rely primarily on the detection of mutations within emb B. However, discordance between emb B406 mutations and phenotypic drug sensitivity questions its clinical significance. This study aims to decipher the association of emb B406 mutations with ethambutol resistance in M. tuberculosis . <h4>Methods</h4> All...

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Literature Corpus work
e5422129-3887-52f6-be16-ceb89939bc1c
DOI
10.1101/2023.03.08.531832
Open publication

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