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Mutations Found in<i>embCAB</i>,<i>embR</i>, and<i>ubiA</i>Genes of Ethambutol-Sensitive and -Resistant<i>Mycobacterium tuberculosis</i>Clinical Isolates from China

1 Jan 2015

Abstract excerpt

To better understand the molecular mechanisms of Ethambutol (EMB) resistance, the mutant hot spot region of five genes (embB, embA, embC, embR, and ubiA) was amplified and sequenced in 109 EMB-resistant and 153 EMB-susceptible clinical isolates from China. Twenty-seven EMB-susceptible isolates were found to have nonsynonym mutations, 23 of which were in embB. The mutations occurred most frequently in embB (85.3%,...

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PMID: 26417605
DOI: 10.1155/2015/951706

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Mutations Found in<i>embCAB</i>,<i>embR</i>, and<i>ubiA</i>Genes of Ethambutol-Sensitive and -Resistant<i>Mycobacterium tuberculosis</i>Clinical Isolates from ChinaPMID 26417605Read ↗

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