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Global Status of Ethambutol Resistance in Mycobacterium tuberculosis Clinical Isolates: An Updated Systematic Review and Meta-Analysis.

Microbial drug resistance (Larchmont, N.Y.) - 1 Aug 2026

Dai Xiting, Wu Hanxin, Zhu Liangyu, Chen Zhiqiang, Ma Weijie, Peng Li, Yang Rui, Luo Suyi, Bao Fukai, Liu Aihua

Abstract excerpt

Ethambutol (EMB) serves as a critical first-line antimycobacterial agent pivotal in the management of Mycobacterium tuberculosis. The emergence of resistance to EMB, primarily driven by mutations in the embB gene, constitutes a formidable challenge to global tuberculosis (TB) eradication efforts. This meta-analysis followed PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines and...

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PMID: 42095672
DOI: 10.1177/10766294261448630

Genes

EMB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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