Article

Quantification of Cerebrospinal Fluid Tumor DNA in Lung Cancer Patients with Suspected Leptomeningeal Carcinomatosis

2024-01-04

Abstract excerpt

<h4>Introduction</h4> Cerebrospinal fluid tumor-derived DNA (CSF-tDNA) analysis is a promising approach for monitoring neoplastic processes of the central nervous system. We hypothesize that analysis of CSF-tDNA in patients with advanced lung cancer improves the sensitivity of leptomeningeal disease (LMD) diagnosis and enables central nervous system response monitoring. <h4>Methods</h4> We applied CAPP-Seq using a...

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Literature Corpus work: e53e6755-3d4c-57cc-b37c-c84d21cdc06e
DOI: 10.1101/2024.01.03.23300646

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