Article

Cerebrospinal Fluid Circulating Tumor DNA Genotyping and Survival Analysis in Lung Adenocarcinoma With Leptomeningeal Metastases

2023-09-05

Abstract excerpt

<h4>Purpose: </h4> The prognosis of patients with leptomeningeal metastasis (LM) remains poor. Circulating tumor DNA (ctDNA) has been proven more abundantly present in the cerebrospinal fluid (CSF), hence, its clinical implication as a biomarker need to be further verified. Methods We conducted a retrospective study of 35 lung adenocarcinoma (LUAD) patients with LM, and all patients collected matched CSF and plas...

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Literature Corpus work: a6be6c1b-4fd5-537c-98e4-4fdb0ce80ab3
DOI: 10.21203/rs.3.rs-3309843/v1

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