Article

XerC is required for the repair of antibiotic- and immune-mediated DNA damage in <i>Staphylococcus aureus</i>

2022-09-04

Abstract excerpt

To survive in the host environment, pathogenic bacteria need to be able repair DNA damage caused by both antibiotics and the immune system. The SOS response is a key bacterial pathway to repair DNA double strand breaks and may therefore be a good target for novel therapeutics to sensitise bacteria to antibiotics and the immune response. However, the genes required for the SOS response in Staphylococcus aureus hav...

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Literature Corpus work: e4dc329c-0f0f-585a-a513-942acdb0b5ae
DOI: 10.1101/2022.09.04.506505

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