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Inhibition of a conserved DNA repair complex promotes susceptibility of Staphylococcus aureus to host defences

2020-01-01

Abstract excerpt

Staphylococcus aureus is a leading cause of serious infections in humans, but treatment can be ineffective due to the emergence of antibiotic-resistant strains. During infection, the most important host defence mechanism against Staphylococcus aureus is the oxidative burst of neutrophils, which involves the rapid generation and release of reactive oxygen species. However, whilst it has been hypothesised that DNA i...

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Literature Corpus work: b41d6407-41ae-5b78-9cb3-a63d2ed65582
DOI: 10.25560/80126

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