Article
Genetic characterization of gram-positive homologs of the XerCD site-specific recombinases.
Journal of molecular microbiology and biotechnology - 1 Apr 2000
Chalker A F, Lupas A, Ingraham K, So C Y, Lunsford R D, Li T, Bryant A, Holmes D J, Marra A, Pearson S C, Ray J, Burnham M K, Palmer L M, Biswas S, Zalacain M
Abstract excerpt
Homologs of the XerCD enzymes, which in Escherichia coli have been shown to be responsible for resolving chromosomal multimers prior to chromosome segregation, were identified in the genomes of Staphylococcus aureus and Streptococcus pneumoniae. Phylogenetic and conservation pattern analysis suggests that the S. aureus gene products are orthologs of XerC and D. A S. aureus xerC null mutant displayed in vitro...
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