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Article

circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner

2022-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Circular RNAs are endogenous long-lived and abundant non-coding species. Despite their prevalence, only few circRNAs have been dissected mechanistically to date. Here, we catalogued nascent RNA-enriched circRNAs from primary human cells and functionally assign a role to circRAB3IP in sustaining cellular homeostasis. We combined “omics” and functional experiments to show how circRAB3IP depletion...

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Identifiers and source

Literature Corpus work
e4d136fb-834f-58a3-b006-569ff85d649d
DOI
10.1101/2022.03.25.485787
Open publication

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