Article
Circular RNA in cardiovascular disease: Expression, mechanisms and clinical prospects.
Journal of cellular and molecular medicine - 1 Feb 2021
Tang Ying, Bao Jinghui, Hu Jiahui, Liu Leiling, Xu Dan-Yan
Abstract excerpt
Circular RNAs (circRNAs) are a group of covalently closed, endogenous, non-coding RNAs, which exist widely in human tissues including the heart. Increasing evidence has shown that cardiac circRNAs play crucial regulatory roles in cardiovascular diseases (CVDs). In this review, we aimed to provide a systemic understanding of circRNAs with a special emphasis on the cardiovascular system. We have summarized the...
Topics
- Biomarkers
- Cardiovascular Diseases
- Disease Susceptibility
- Gene Expression Regulation
- Gene Regulatory Networks
- Humans
- MicroRNAs
- Molecular Diagnostic Techniques
- Phenotype
- Prognosis
- RNA Interference