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Article

Circular RNAs in stem cells: from basic research to clinical implications.

Bioscience reports - 28 Jan 2022

Lu Hui-Juan, Li Juan, Yang Guodong, Yi Cun-Jian, Zhang Daping, Yu Fenggang, Ma Zhaowu

Abstract excerpt

Circular RNAs (circRNAs) are a special class of endogenous RNAs with a wide variety of pathophysiological functions via diverse mechanisms, including transcription, microRNA (miRNA) sponge, protein sponge/decoy, and translation. Stem cells are pluripotent cells with unique properties of self-renewal and differentiation. Dysregulated circRNAs identified in various stem cell types can affect stem cell self-renewal...

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Identifiers

PMID: 34908111
DOI: 10.1042/BSR20212510
PMCID: PMC8738868

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