Article
Functional landscape of circular RNAs in human cancer cells
2025-03-28
Abstract excerpt
Circular RNAs (circRNAs) constitute a novel class of noncoding RNAs showcasing distinct tissue- and cell-specific expression patterns. Despite the extensive profiling of circRNAs, their individual functions remain poorly understood. To fill this gap, we designed a genome-wide library of 65,300 shRNAs, targeting 9,663 clinically relevant circRNAs and 3,981 of their linear parental genes, and conducted functional sc...
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Identifiers and source
- Literature Corpus work
- 72567849-7ac5-578e-a71e-c993b809abae
- DOI
- 10.1101/2025.03.24.645016