Article

Addressing the antibody germline bias and its effect on language models for improved antibody design

2024-02-07

Abstract excerpt

<h4> A bstract </h4> The versatile binding properties of antibodies have made them an extremely important class of biotherapeutics. However, therapeutic antibody development is a complex, expensive and time-consuming task, with the final antibody needing to not only have strong and specific binding, but also be minimally impacted by any developability issues. The success of transformer-based language models in...

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Literature Corpus work: 1ef8c626-bde2-5fc2-b13d-2b65ba0e3e44
DOI: 10.1101/2024.02.02.578678

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