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Applications of single-cell and bulk RNA sequencing in onco-immunology

16 Apr 2021

Abstract excerpt

The rising interest for precise characterization of the tumour immune contexture has recently brought forward the high potential of RNA sequencing (RNA-seq) in identifying molecular mechanisms engaged in the response to immunotherapy. In this review, we provide an overview of the major principles of single-cell and conventional (bulk) RNA-seq applied to onco-immunology. We describe standard preprocessing and...

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PMID: 33866228
DOI: 10.1016/j.ejca.2021.03.005

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