Article

Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8 <sup>+</sup> T cells during CNS chronic infection

2024-07-30

Abstract excerpt

<h4>ABSTRACT</h4> Tissue-resident memory T cells (Trm) are essential for regional immunity in non-lymphoid tissues. Although single-cell transcriptomics have revealed Trm heterogeneity in various diseases, the molecular mechanisms behind this diversity are unclear. To investigate this, we used Toxoplasma gondii ( T. gondii ) infection, which persists in the central nervous system (CNS) and is controlled by brai...

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Literature Corpus work: e3fad8e3-e1b8-5020-ac46-709a5615998f
DOI: 10.1101/2024.07.30.605547

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