Article

RUNX3 is a Potential Marker for Vaso-Occlusive Crises by a Whole Blood Transcriptomic Analysis in Sickle Cell Disease

2024-11-06

Abstract excerpt

<title>Abstract</title> <p>Sickle cell disease is the commonest hemoglobinopathy which results from a mutation in the β-globin gene of hemoglobin and predisposes to painful Vaso-occlusive crisis (VOC) and multi-organ dysfunctions. The huge phenotypical variation makes it challenging to define and predict the disease severity and outcomes. This study aimed to characterize the whole blood gene expression profile us...

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Literature Corpus work: e3c24846-b707-51b8-80dd-6497a055a087
DOI: 10.21203/rs.3.rs-5397806/v1

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