Article

Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites: implications for genomic RNA packaging

2025-01-12

Abstract excerpt

Retroviruses cause significant diseases in humans and animals, including the acquired immunodeficiency syndrome and a wide range of malignancies. A crucial yet poorly understood step in the replication cycle is the recognition and selection of unspliced viral RNA (USvRNA) by the retroviral Gag protein, which binds to the psi (Ψ) packaging sequence in the 5’ leader, to package it as genomic RNA (gRNA) into nascent...

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Literature Corpus work: e3b0e5a4-a5c3-5df9-b836-41b9a7a67a0a
DOI: 10.1101/2025.01.11.632546

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