Article

An infectious Rous Sarcoma Virus Gag mutant that is defective in nuclear cycling

2021-04-17

Abstract excerpt

During retroviral replication, unspliced viral genomic RNA (gRNA) must escape the nucleus for translation into viral proteins and packaging into virions. “Complex” retroviruses such as Human Immunodeficiency Virus (HIV) use cis-acting elements on the unspliced gRNA in conjunction with trans-acting viral proteins to facilitate this escape. “Simple” retroviruses such as Mason-Pfizer Monkey Virus (MPMV) and Murine Le...

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Literature Corpus work: 0c83d2db-41b6-5252-a294-c2524fb437af
DOI: 10.1101/2021.04.16.440250

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